Been doing a lot of research on this the last few days before my sub install. The 10 speaker Centerpoint Bose system in upper trims has the Audiopilot feature that compensates for road noise when listening to music. Certain GM vehicles also have Bose Active Sound Management which uses the audio system to offset or enhance noise - Engine Harmonic Cancellation or Engine Harmonic Enhancement. Finally Bose has Quietcomfort Road Noise Control or RNC. This is newer version of ASM.
All of these systems rely on a series of microphones in the cabin to hear and send signals to offset noise with speakers. I believe the newer 18+ vehicles with the Centerpoint ONLY have the Audiopilot feature that can be turned off in the head unit settings. I speculate that the ASM was in the earlier models, but was removed due to the famous "buffeting" problem, but I dont know for sure. Long story short - turn off AP in settings; if that doesn't work, disable the mics. I have seen a harness on YT that does this at the rear Bose amp, and I have seen people just pulling the mics and cutting the wires. The mics are in the 3rd plug down, so maybe you can pull it first to try it out.
As a final note - 9 speaker Bose like mine in the LT do not have Audiopilot...