“Pure” (read: straight, as not even UHP Nitrogen is 100% pure — there will always be impurities in the gases) Nitrogen is lighter than atmospheric air (which is already over 3/4 nitrogen already), and due to it’s chemical makeup, may keep a tire inflated for longer versus atmospheric air. Despite misinformation, when a tire is filled with “straight” nitrogen, it has less resistance from friction versus atmospheric air. The result is a marginally better and often negligible benefit in gas mileage and perhaps tire life.
Nitrogen is inert, you can add it to air; you can add air to nitrogen, or have any mixture percentage of the two in a tire at any given time. Obviously, you will not receive the marginal benefit of n2 in the tires if it’s being cut with atmospheric air anyways.
I’ve done my own calculations and over a lifetime, a home rig of n2 costs far less than filling up w/ air at gas stations. Actual results may vary depending on more factors that can be listed here. The cost for a home rig is cheap once you get the initial investment out the way.
Here’s mine:
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Bottom line: any reason NOT to do it? No. But if you’re expecting nitrogen to be some sort elixir that will improve gas mileage tenfold, you will be disappointed.