In the GMX550 instructions it says:
"**During the time that you are using the 60 second NAV IN MOTION feature to input an address, active map tracking is not occurring (if you switch back to the map, the map will not be moving or pinpointing your exact location). Standard navigation functions will automatically return after 1 minute or you can turn off the NAV IN MOTION function using your steering wheel buttons to immediately resume normal nav operation. Also, if you are using OVERRIDE MODE 1 or 2, the GMX550 needs to block navigation tracking when you activate the DVD IN MOTION function. Simply turn off DVD IN MOTION if you switch back to the map during DVD play for normal
operation."
It looks like the system is by default using the OVERRIDE MODE 1 setting.
So if you haven't removed your lockpick yet, maybe you should try turning off the NAV in motion after you finish entering your destination and see if the voice prompts come back.