I have a 2003 Sierra Denali with a 4l65e and 4.10s. It is by far the highest accelerating, best driving truck we have. I have a 2004 Silverado 2500 that was never reprogrammed for oversized tires, so it is a dog off the line ($l80e/3.73s). I have a 2005 Suburban 2500 with the 4l80e and 3.73 gears. All 3 are 6.0s.
I list the above out to let you know I have some experience with these combinations. Because my experience has been that the 4l80e has a mechanically higher gear than the 4l60/65, such that the shift to 2nd takes longer in a 4l80. Keep in mind I realize the Sierra Denali is a lighter vehicle and have taken that into account.
From this article:
4L80e Transmission—All You Need to Know
"The 4L80e uses four forward gears and one reverse gear in the following ratios! First gear:2.48, second gear:1.48, third gear:1:0, fourth gear:0:75, and reverse gear:2.07. It has a maximum input torque of 440 lb-ft and a maximum output torque of 885 lbs-ft with a vehicle weight rating of 800 lbs."
From this article:
4L60E Identification: Complete Guide
View attachment 424364
From this article:
4L65E TRANSMISSION SPECS AND UPDATES
"The 4L65E transmission has a weight of 194.6 pounds. It’s gear ratios for the first gear, second gear, third gear, and fourth gear are 3.059-to-1, 1.625-to-1, 1-to-1, and 0.0696-to-1, respectively. What’s more, the 4L65E features five-pinion planetary carriers."
According to those articles, the 4l60 should be faster off the line, faster in 2nd gear, the same in 3rd gear, and a little slower in 4th. The 4l60 also has the advantage in verse, with a 2.29 gear vs. the 4l80 2.07.
This does fly out the window if you regear, and will be modified by the final drive ratio.
If you have a better source of information, please share it. I don't mind being wrong, but I want to have the information to back up what I say. I'm a member of about 12 truck/SUV forums. Many of which are not as nice as the folks here.
[EDIT] Something I don't recall seeing in this thread that makes all the difference in the world are the programmed shift points. Having a perfectly geared set up and crappy shift points can really ruin your day.