Check to see if an exhaust manifold bolt snapped and is missing. Checked for an exhaust manifold leak, as well as the flange or the downpipes connect.
It's only normal for the new lifters to make a ticking sound at first startup, usually just a minute or two until they are fully pumped up with the oil pressure.
Did a shop rebuild this? If so, take it back to them. Often it's the preload by not measuring correct pushrod length. Very important on a rebuild where distances change from surfacing the head,. If a shop did this rebuild, ask them if they used genuine GM lifter trays. Aftermarket ones are problematic. I would also want to find out what lifters they used. There's a lot of very cheap aftermarket made in China ones.