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You would need to use adapters for the knock sensors and I think the crank sensor. They are different generations with different injectors so either use Gen III stuff or use the right adapters to make it work. Oh, the crankshaft in a Gen IV has a different reluctor wheel that doesn't talk to Gen III computers, Lingenfelter and maybe some others have adapters for that as well.I am considering putting a 6.2 into my 03 yukon. Any year models that would be easier? I know it will have to be tuned, but will I need a different harness? Any insight would be great before I pick up a long block this week.