I know you say you replaced the fuel pressure regulator, but I’m suspect of it still.
one possibility for misfires on 1 and 8 is liquids in the intake, weather it’s caused by gas, oil or something crazy.
5 and 6 are near where the vacuum line for the regulator connects.
occasionally pulling lots of fuel, then evening out, especially after a hot soak, would indicate a regulator.
im not saying replace it, but just check it a couple more times. Just pull the vacuum hose off, checking for fuel. If it’s dry, twist the regulator to point the port down and make sure everything is dry.