Directions on back label of Prestone Dexcool 50/50. Top off: Fill overflow tank to Max level with 50/50 Prestone. Drain and Fill: 'Requires 2 gallons of Prestone 50/50'. Only the Concentrate has mixing directions on the back label.
I was just using 2 gallons as example to illustrate the cost. The 5.3 needs 4. My point was it's usually much cheaper to buy full strength and dilute it yourself.
I might agree with a couple of gallons of 50/50 IF you're just letting things drain and you're not doing a good job of draining the block. Really, though, while you're at it why not flush the whole thing and have all-new antifreeze mix instead of mixing new with old?
The listed capacity for the 5.3L V8 cooling system is around 16 quarts. That's 4 gallons for those of you who are mathematically challenged. A 50/50 mix would take 2 gallons of straight antifreeze, not prediluted. Personally I like to start with about a 60% antifreeze mix in the entire system in case I need to add just water in a bind.
Agreed on the flush. Here's my method, that avoids needing to be crazy on draining (like removing the block plug), and is easy on math (knowing how to divide the system capacity by 2):
1. Drain that puppy from the lower radiator hose AND the hose from the pump. Put it back together and fill it with the garden hose.
2. Run it. Drain it. Fill it. Run it. Drain it. You get the idea. I do it until it's draining good and clean. Maybe 6-8 times. Anything left in the system after the last drain will be "clean" water.
3. Add full concentrate coolant based on 50-60% of the system capacity.
4. Add distilled water to full.
This removes any guess work, as you know the system capacity and exactly how much full concentrate coolant you put into it. The rest is obviously water, either from your garden hose or your distilled final fill.