You would have to drill the hole in your fenders and quarters to use the mounting OEM mounting hardware. Around the top of the flare is a metal piece that has bolts attached to it.
I did this upgrade with out the OEM bolts and without drilling holes.
If you have the door trim running the length of the truck, you will need to remove and shorted some of them or replace from the other truck.
What I did to secure the top of the flares to the truck was to use 3M auto trim tape. I used the 5/8 wide tape which was a little bit wide, but it has more adhesive. Also, make sure you use the screw that come with the flares.
The flare use more screw holes than the chrome trim. The extra holes are already drilled but filled in with flexible sealer and painted over. They were easy to find.