The k2xx trucks are not designed for the AGM battery. I was told this by a Cadillac expert that knows Escalades. I would get the AC Delco gold battery which is designed for your truck. They come with a 40 month warranty and sells for less than $170. You need a special charger for AGM. You can do research on google and see for yourself. Would you want to keep a battery for more than 40 months and spend $400? My original battery lasted 4 years and 5 months.
the Interstate AGM is around $160-170 at Costco I have one in my 18 and have had it in there for about 2 years now with no issues
I have also ran AGM's in all my other trucks since around 2006 and like all batteries of any kind they eventually go bad, the difference is a AGM will typically just start to get weak where as a typical acid battery will simply die and leave you stranded out of the blue.
I have 2 AGM's in my 2012 as well and another in my wifes 05, and one in my old 03 that I sold to my sister, I had them in my 00 as well
to answer the OP's original question, "maybe" it really depends but there are only 2 things that will typically need to be done.
1. is the drivers window if it needs to be recalibrated after a battery change or disconnect then you may get a message in the DIC saying it needs to be calibrated to do this all you have to do is push the window switch down and continue holding the button down for 5 seconds, then do the reverse and put the window up and continue to hold the button for 5 seconds. done.
2. the compass may show "CAL" instead of n/s/w/e in this case you just need to go out in a open area and drive in a few complete circles one direction and then turn around and drive in a few circles the opposite direction. done (sometimes you may need to do this a second time if the "CAL" comes back in the compass.
