In 2001 an updated version, the 4L65-E, was introduced. Five-pinion planetaries, along with a strength-improved output shaft, were improved to withstand the 300+ ft·lb (over 400 N·m) of torque of the 6.0 Vortec engine.
So a good tranny shop could update to 5 planetaries and input shaft and pretty much have a 65e.
True, 80e gearing is:
Gear Ratios are:
First Gear - 2.48 to 1.00
Second Gear - 1.48 to 1.00
Third Gear - 1.00 to 1.00
Reverse - 2.07 to 1.00
and 60e is:
First - 3.059:1.0
Second - 1.625:1.0
Third - 1.000:1.0
Fourth - 0.696:1.0
Reverse - 2.294:1.0