I'm no expert, but am getting the thought that 305/45-22 might be pushing it a bit on a stock ride height Hoe.
Maybe 285/45-22, or 305/40-22 instead would be a safer bet? You've probably already studied tire specs, and I'm thinking there may be indeed a need for some height tweaking. Usually the back isn't the problem, it's the front. I'm sure offset can be important and critical, and not necessarily for outboard clearance, but as well as inboard clearance too.
I'm curious too, if anyone here knows the actual difference in tracking width from the front, to the rear of such Tahoes. Isn't the '99 considered a NBS versus my 1997 Hoe?
I understand what you say about a spacer, the question I would have, would be how thick? 1/4"? 3/8"? or ?
I know all too often, one has little in the way of experimentation with such sizes when we walk into a business, that we commit, buy, then find out later about issues, which of course is no fun.
Mark