I'm using the Bose Luxury amp to run the 4 JBL door speakers, the 2 A-pillar tweeters and the 2 speakers in the back by the lift gate. I have a JL 10" sub in an MTX Thunderform enclosure behind the rear left panel running off a Soundstream Picasso Nano 450 watt amp. I read up on the different Bose amps and if you're lucky enough to have the Lux model, it's a great amp. The non-Lux is just OK. You'll need to do some research on the subject if you want to learn about the difference. From what I understand, the Lux is "smart" which allows the signal to be adjusted over the vehicles data bus, so it's cleaner and also allows for a theater or surround effect. I forget how to figure out if you have one or the other but I know the Denalis have the Lux.