The hub WILL fail if it's a 4WD hub with the CV shaft removed. I personally know because I was in a vehicle that it happened to. At the dealership, I worked on a 05 Silverado with front end noise. Thought it was a hub and replaced it. Noise persisted, so I removed the CV shaft and drive it out to see if the noise went away. As I was driving back into the shop, the wheel fell off and the hub was destroyed. DO NOT DRIVE WITHOUT CV AXLES WITH 4X4 HUBS!!!!!! I believe the 2014+ trucks made a hub change where it doesn't matter if it's 2WD or 4WD, but those are made different. Don't risk your life or the life of others!! This has been proven MANY times, the GMT800 4WD hubs NEED the CV shaft there for support.