You will ned a wally 450 pump, larger primary fuel line and a GM hot wire kit for fuel pump.
Use your oem primary as your new return line.
You will need to easily double if not triple your injector size.
As well as need a good fuel regulator.
Oem rails will be fine.
Its very easy to do, just costs some money.
Go to performancetrucks.net and dig in the forced induction section. 70% of those guys run E85 with their blowers. Its very common.
Yess get ready to loose A TON of mpg.
E85 on even a NA engine setup require 30% more fuel, to make the same AFR.
Consider doing a methanol kit instead. It wont allow for as much boost, but will probably get you where you want.
Its cheap and can get you some really good results. @
JennaBear for a meth kit, she runs one on her ride. Im sure she can also throw ya a deal if you talk all sweet like.