Your STFTs are fine. Running E85 in a non-flex engine is going to cause lean codes. Your non-flex injectors are not going to be able to flow enough to make up for the E85. You might get by with a mix of E85 and gas to make, say, E30, but you'll be watching those STFTs go up.
He will be fine to mix a 1/4 tank of regular to 3/4 tank e85. Yes the trim will max out, but that is the point. To full duty cycle the injectors and run the most ethanol through them as possible because it is a very good cleaner. I ha e done it in my nonflex Silverado and yes it will guzzle the fuel, just light cruising will not blow it up.
As suggested before, run E0 (non-ethanol or ethanol-free) if you can find it and, if you think the injectors are not flowing as they should, use a good fuel system cleaner like BG44K, Techron, etc. for a few tankfuls. Others will have more suggestions on good cleaners. But I'm not convinced that's the cause of your slightly high LTFTs.
E0 while great in a vehicle that can use it, will typically cost more per gallon. And not fix his issue.
Get a scanner on it to see what the system thinks the current alcohol content is, just to verify. We're working in the dark here.
A scanner will not help determine the ethanol content. It will only show lean or rich.
1. It is an 06 if his name is a clue, therefore it wouldn't have a flex sensor as GM went to a " Virtual Flex" Strategy in late 05 where the ECM calculated ethanol content by Maf and O2 sensor variables.( Basically it guessed at what was in the tank, whelich ended up problematic) So a leaky intake gasket or failing O2 sensor could think you are running e15 to e85 even if you had regular in the tank.
2. He said it It was not flex, so it doesn't even have that algorithm to look at to assume ethanol content. It is just looking to get to 14.7:1 afr with regular 87 octane.
3. Only the flex fuel capable vehicles have a default percentage and that is 38.5 percent ethanol. This again is not present in the non-flex programming.
Other things that can cause trims to be off, incoming air temp sensor, coolant sensor, maf and map sensors. These all are in the calculation so even if they aren't off enough to set a code, they can tweak the air fuel to a point.