This all sounds like greek to me.
I've seen 305-40/22's rub on a 2007 Denali, with 22x9.5 wheels (+25 offset BR Pondoras)
Yep, that stupid plastic Lip GM decided to throw on the front fenders, what use they had, I have no idea?
And, the question begs, is a 305-45/22 suitable for a narrow 9" wheel?
Sounds like lots of different installations, where nothing is set in stone, and let's just fly by the seat of our pants, figuring what works, and learning the hard way what doesn't.
It's why I put off buying wheels-tires for my '97 Tahoe, I'm so freaking confused the further I go, I truly can't find my ass with two hands about such.