Your '19 has V4 mode (still?)
Your '21 has V8 mode, V7 mode, V6 mode, V5 mode, V4 mode, V3 mode, AND V2 mode.
(Not sure about 1-cylinder mode; the single cylinder would need to change each time to balance crank stresses.)
GM designed the OE exhaust to minimize audible detection of the mode changes.
Your exhaust is likely making it more audible.
If your mods released more power, then yes, that might allow even more use of cylinder deactivations.
I do not believe the ECM allows use of DFM in neutral, but I could be wrong.
In any case, are you considering the disabling of the AFM / DFM subroutines in your vehicles?
How long do you want to keep your '21 Denali and your '19 Silverado?