The Transmission Control Module (TCM) learns as your drive, following your tune. As
@swathdiver stated, drive the truck, and in a few days, your TCM will have completed its learning phase. The most noticeable improvement is how the transmission performs when you step on the pedal.
For example, you will note in a WOT test that your transmission will allow the engine to go completely to the red line, before shifting. The stock tune allows the engine to go only to 5500 rpms max, before shifting, thus not taking advantage of the last 500 rpms at the top of the power curve.
There are other performance improvements you will note, as you become familiar with the new tune. My tune was set up for 93 octane (stock setup was for 87 octane, though 91 octane was 'recommended'), so my performance improvement was quite noticeable.