I am at 45K miles replaced pads and rotors with Rock auto Powerstop Z36 carbon/ceramic pads and zinc coated drilled and slotted matching rotors , about $400 in parts stop Great will have to chime back in a few months for long term test.... I also installed Michelin Premier LTX tires from Costco , I like the tires but have had to replace my right rear tire 3 times , 2 large bolts and one time was my fault , the Chicago streets are tough luckily the first 2 times Costco didn't charge me a dime , on the last one I only had to pay $ 40 .....
My 2015 Denali was making noise from the rear brakes like one of the wear indicators was making contact with the rotor. I could see the outside pads through the wheel and they still had at least 50% of material left on them. Knowing that sometimes the inside/outside pads can wear differently from a caliper becoming stuck, I pulled both rear wheels to inspect. I found one of the hardware components (that retains the pad) to be bent and making contact with the rotor. I easily straightened the part, cleaned/lubed the calipers and re-installed.
I had researched the Powerstop Z36 pads for replacement with the Powerstop rotors (non drilled/slotted) in case I needed replacement. My reason for going straight to Powerstop is that I purchased a brand new Audi S6 back in February this year. The factory pads produce what is beyond a ridiculous amount of dust and are prone to squealing in freezing or below temps. I had a 2013 Audi S4 that I purchased new (traded for the new S6) and I replaced the brakes on that car early as well for the same reasons. While wanting to retain factory brake performance and initial bite but with much less dust, I was recommended the Powerstop Z26 pads through the Audi forums. The Powerstop pads deliver on every level...... hardly any dust, great bite/modulation (even from triple digit stops) and zero noise.
I would not hesitate to recommend their products to anyone looking for replacement options. I have also used their brake parts on other vehicles with positive results.
As far as tires......... Another solid vote for the Defender LTX. I drove my Denali through the first winter (which was mild with little snow) after buying it new 10/1/2015 and was very unhappy with the Bridgestones (factory 22" wheels). I purchased new Defender LTX tires before the next winter of 2016 and it was a night/day difference on all levels.