One thing to consider is that your Denali, even though rated to be able to tow up to a certain maximum amount, cannot tow the full amount of its rating, SAFELY for you, your vehicle engine or for folks on the road around you when you tow.
The tow rating on your Denali is for an empty towed vehicle and an empty towing vehicle - it does not include more than 1 occupant, gas, accessories you've added, hitch weight, tongue weight and the trailer weight posted as the final weight does not include anything that you typically include in a trailer when going somewhere with it. To SAFELY tow, for you, your engine, and occupants of the roads you travel on when you tow, the general rule is to keep what your towing below 80% of your capacity to allow for all those extras, but you have to maintain payload capacities, axle capacities since a proper weight distributing hitch throws weight to the front and rear, and GCVWR capacities as well.
And once within those capacities, yes, you do have to know and maintain trailering speeds wherever you travel.
There's a lot more to towing that hitching a trailer up and driving down the road. Your RPMs, air brake effect, etc. won't mean a thing when you are driving down the road way over capacity at unsafe speeds and yes, that would prematurely wear your engine.