I have a 2016 Z71 with about 5K miles. No vibration, no pressure changes, and the changes into V4 is invisible to me, but I do notice the slight booming when hitting potholes, speed bumps, expansion joints etc. I have crossbars with surfboard pads, 275/65-18 Nokian AT Rotiivas, and a GM\Borla Cat-back exhaust.
I can imagine the suspension booming is miserable with 22" wheels, as the Suburban does not seem to have any sound deadening - it is loud. Louder than my 2014 Accord with 235/45-18's over bumps, and like a chuckwagon compared to my wife's 2008 Range Rover. I still love my Z71 despite this uncouth characteristic.